Botanicula follows the industry standard rules for adventure puzzle games: the game won't let the player characters die and won't let the player do anything that prevents him from solving the puzzles and winning the game.
Where Botanicula differs is in the puzzle controls. In Myst, nearly all of the puzzle controls are familiar and simple: buttons, levers, sliders, switches. In Botanicula, most of the controls are the bizarre organisms that populate the game world. On a tablet, a player operates Botanicula's controls by the same tapping and dragging used in other apps, but the player must find the organisms that can be manipulated, which are sometimes hidden behind leaves, and then must figure out how to manipulate them. That is the bulk of the gameplay. Once the controls are identified and the way to operate them has been discerned, there usually isn't much more in the way of puzzle solving to do.
There was also one annoying and pointless arcade mini-game that must be won to continue, something that has no business being in a puzzle game. After all, the market is already saturated with arcade games for people who like them. I don't know why Amanita keeps putting at least one arcade mini-game in each of their puzzle games, but I wish they would just STOP. Minus one star for that.
The puzzles aren't likely to stump experienced gamers for long, but gameplay is surprisingly satisfying. The graphics are colorful and have a quirky appeal. The sound effects for some puzzles are annoying, but on the whole, the game has a pleasant, relaxing vibe.